What is Mysimba?

Mysimba is a combination of two medicines (Bupropion and Naltrexone) which has been developed to help people who want to lose weight, and who are overweight (with a Body Mass Index of 27 or more) and have additional health risk factors. There are many reasons why people may experience weight gain other than hunger such as difficulty in managing portion size and stress or anxiety related eating. All of which may help trigger unwanted weight gain. The medicines in Mysimba work to help the brain regulate your appetite and change the feelings you may have when eating food.

Cheapest Mysimba tablets in the UK?

We think we're the cheapest in the UK. Let us know if you find out different. Our price is the price you pay, there are NO other charges. Video consultation at your convenience, and free delivery of your medication. Mysimba is a type of weight loss aid medication and should only be taken under doctor’s recommendations, and when lifestyle changes have not worked. You need a prescription from a prescriber in order to buy this medication online which Hive Pharmacy does provide within this service.

How does Mysimba help with weight loss?

In some patients, obesity is often related to the brain, many people eat when they’re stressed or have excessive hunger and food cravings. Mysimba contains two active ingredients, naltrexone hydrochloride and bupropion hydrochloride, which work on the areas of the brain which control food intake and energy expenditure. These ingredients work together to change how you feel about food and appetite. Reducing your appetite results in less food intake which ultimately leads to weight loss, especially with a low calorie diet and regular exercise. Mysimba helps to control your food cravings and makes you feel less hungry so you can reduce your calorie intake and reduce your weight.

Who is Mysimba suitable for?

If you have been medically diagnosed as obese and you are over 18 years of age, Mysimba may be a suitable solution for you providing you have tried other methods such as exercising and having a low calorie diet but to no avail. If dieting alone has not proved successful for you, Mysimba can assist you in losing extra pounds to bring you to a healthy weight. However, you should always consult a doctor before taking this medicine to ensure your suitability.

Mysimba patient information leaflet

https://www.medicines.org.uk/emc/files/pil.2684.pdf

What do I need to know for the consultation?

We will ask you:

• Your weight
• Your height
• Your blood pressure (actual figures)
• do you have high cholesterol
• do you suffer with sleep apnoea
• do you have diabetes
• are you pregnant or breastfeeding
• allergies to medications
• do you have any eating disorders
• are you dependent on any drugs such as opiates
• do you have galactose intolerance
• Do you have any hepatic (liver) impairment
• Do you have a current or past history of cerebrovascular disease, transient ischaemic attack (mini stroke) or stroke
• Do you frequently use cocaine or other recreational drugs
• Are you a heavy drinker
• Do you have a condition that causes seizures or do you have a history of seizures
• Are you taking or have you recently stopped taking sedatives or medicines to treat anxiety (e.g. benzodiazepines)
• Do you have a current or past history of severe depression, suicidal thoughts, generalized anxiety disorder, psychosis, or any other psychiatric disorder
• Do you currently have depression or are you taking medication for depression
• Do you have active coronary artery disease (e.g., ongoing angina, recent heart attack)
• Do you have a brain tumour
• Do you suffer from renal (kidney) impairment
• Do you have a medical condition that may contribute to your weight gain
• Do you have any brain or nervous system disorders
• Confirm if you are currently taking any medication (over the counter or prescription)
• Have you previously been treated for any other medical conditions
• Do you have a current or past history of a head injury or trauma
• Do you have any heart or circulation problems
• Do you have a history of (non-severe) depression
• Do you smoke

Further weight loss support

✓ If appropriate, the Your Weight, Your Health booklet produced by the Department of Health, available at:
http://www.htmc.co.uk/resource/data/htmc1/docs/How%20to%20take%20control%20of%20your%20weig
ht.pdf ✓ Information on healthy eating. For example, The Eatwell Guide, available at: https://www.nhs.uk/live-well/eat-well/the-eatwell-guide/ ✓ The patient information leaflet (PIL) for any medication that is administered/supplied. These may be found
at: https://www.medicines.org.uk/emc/ ✓ If appropriate, the NHS weight loss guide, available at: https://www.nhs.uk/live-well/healthy-weight/start-the-nhs-weight-loss-plan/ ✓ Information on weight loss support group services and where the patient can find these. These may be
found at: https://www.nhs.uk/Service-Search/Weight-loss-support-groups/LocationSearch/1429

eTool consultation or the patient can access the consultation details from their patient account.
✓ General information on obesity and the health-related risks.

What happens after the consultation?

If treatment is appropriate, we will send your medication by post so that you can start your medication. Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. The initial dose is usually one tablet (8 mg naltrexone hydrochloride / 90 mg bupropion hydrochloride) once a day in the morning. The dose will be gradually adapted as follows: • Week 1: One tablet once a day in the morning • Week 2: Two tablets every day, one in the morning and one in the evening • Week 3: Three tablets every day, two in the morning and one in the evening • Week 4 and onward: Four tablets every day, two in the morning and two in the evening. The maximum recommended daily dose of Mysimba is two tablets taken twice a day. After 16 weeks and each year after your treatment initiation, your doctor or pharmacist will evaluate whether you should continue to take Mysimba. Mysimba may be discontinued by your pharmacist after 16 weeks if you have not lost at least 5 percent of your initial body weight. We may also recommend stopping treatment if there are concerns about increased blood pressure, or other concerns with the safety or tolerability of this medicine.