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Mepacrine Hydrochloride

Updated: Jan 15, 2021

The main uses of mepacrine are as an antiprotozoal, antirheumatic and an intrapleural sclerosing agent.

Antiprotozoal use include targeting giardiasis, where mepacrine is indicated as a primary agent for patients with metronidazole-resistant giardiasis and patients who should not receive or can not tolerate metronidazole. Giardiasis that is very resistant may even require a combination of mepacrine and metronidazole.

Mepacrine is also used off-label for the treatment of systemic lupus erythematosus, indicated in the treatment of discoid and subcutaneous lupus erythematosus, particularly in patients unable to take chloroquine derivatives.


Many UK pharmacies are struggling to obtain this medicine, but don't worry, Hive is here to help. If you require this medication, ask your GP to prescribe this way for example:

"Mepacrine Hcl 100mg tablet (Special Order)

Take one three times daily

30 tablets"

If you're unsure whether your prescription is valid, send a photo to our dispensary team using the whatsapp number: +44 7828 884035

Then post the prescription to us at the following address:

Hive Pharmacy

23 Edinburgh Drive


TW18 1PJ

Once received, we will busily dispense the medication for you and post it to you by Royal Mail, for free.

Learn more about this service:

Read about Hive



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