Food Intolerance & Diet DNA and Nutrition Requirements

Diet and Nutrition

Understand how your body metabolises certain nutrients and what type of minerals or vitamins it may require. Your Nutrigenetic profile will enable you to adjust your food intake in line with the way your body absorbs and converts these nutrients.

 

Lactose Intolerance

Lactose intolerance is one of the most common intolerances in the world. Milk and dairy products contain a natural sugar called lactose, which is broken down by a protein called lactase in the small intestine. Your ability to produce lactase and tolerance to lactose is affected by your genetics. The test will determine your ability to produce lactase and tolerate lactose in your digestive system.

Gene tested: MCM6

Fat and Glucose Metabolism

Fat regulation is essential in ensuring fat is broken down efficiently, which could otherwise lead to conditions such as altered lipid levels, known as dyslipidemia. This test would determine your sensitivity to fat intake.

Genes tested: PPARG and ADIPOQ.

Caffeine metabolism

Caffeine is a natural substance found in coffee beans, tea and carbonated drinks. Short term caffeine intake is associated with increased heart rate and a hyper-alert state, these symptoms become less pronounced with long-term caffeine intake. The test will determine the rate of caffeine degradation in your body.

Gene tested: CUP1A2‍

Alcohol response

Alcohol has a different effect on each person. Excessive long-term alcohol consumption is associated with developing cardiovascular disease and can negatively impact health and fitness. Genetics are vital in determining adverse side effects of alcohol and how quickly alcohol can be broken down and flushed out of our system. The test will show you how quickly your body processes and eliminates the toxin enabling you to manage your intake accordingly.

Gene tested: ADH1B

Folate (B9), Vitamin B12, Vitamin D and Vitamin A

Folate, also known as Folic acid or vitamin B9, is a Vitamin required to make DNA and vital for many other processes. Folate cannot be made by the body so needs to be consumed through the diet. If folate levels are not high enough in your diet, you can develop folate deficiency. The test will determine your ability to process folate.

Gene tested: MTHFR

Vitamin B12 is required in the production of DNA, amino acids, fatty acids and is essential in other processes. Vitamin B12 cannot be made by the body so needs to be consumed through the diet. If these levels are not high enough in your diet, you can develop Vitamin B12 deficiency. The test will determine your ability to metabolise Vitamin B12.

Genes tested: FUT and TCN1

Vitamin D can be obtained by absorption from sunlight and diet. Enzymes in the kidney and liver, then activate vitamin D. Deficiency of the vitamin may cause muscle pain, bone pain and increased fracture risk. The test will determine your ability to break down Vitamin D.

Gene tested: GC

Vitamin A regulates growth, bone remodelling, vision, cell growth and immune system function. Vitamin A deficiency is rare but can result in poor vision, weak immune system and increased chance of infection. The test will determine your ability to process Vitamin A.

Gene tested: BCMO1

 

 

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Body & Weight Management

Get personalised recommendations on how you can adopt alternative dietary options and routines to achieve a more balanced and healthier lifestyle.
This test will also enable you to understand the way your body converts sugar and how sensitive it is to calorie intake.

 

Feeling Full and Hunger Response

After food consumption, a hormone called leptin is released which acts on the brain to suppress hunger, making you feel full. Some individuals may continue to feel hungry after eating, due to a genetic variation. This can lead to higher food intake and weight gain. The test will determine your satiety response and the chance of obesity.

Genes tested: LEPR, SH2B1, MC4R

Another protein called NYP acts on the brain’s appetite centre to stimulate hunger which contributes to increased food intake and weight gain. The test will determine your hunger stimulation response and the chance of obesity.

Gene tested: NYP2R

Energy Metabolism

Decreased energy metabolism contributes to increased weight gain. This test will determine the relationship between energy metabolism, appetite and chance of obesity.

Gene tested: PCSK1

Food Pleasure Response and Appetite

Hormones control the brain's pleasure and reward centre. A genetic difference in one hormone receptor may lead to a smaller pleasure response despite having eaten a meal. A smaller pleasure response may increase the desire to consume more food in order to feel more satisfied.  The test will determine how the chemical Dopamine controls your brain’s pleasure and reward centre. ‍

Appetite is controlled by a hormone called Ghrelin. The hormone is involved in increasing appetite to indicate that it is time to eat food. The test will look into how your Ghrelin levels affect your eating behaviour.

Gene tested: FTO

Binge Eating and Snaking Behaviour

The protein NMB regulates food intake and can influence binge eating. Leptin on the other hand is a hormone that acts on the areas of the brain responsible for hunger. Changes in leptin function can determine your snacking behaviour and response to food intake. This test will identify your NMB and leptin predisposed levels and your susceptibility to binge-eating and increased snacking behaviour.

Gene tested: LEPR and NMB

Sugar Sensitivity (Sweet tooth)

Sugar sensitivity test looks at an individual’s increased preference for sweet foods. Decreased sensitivity can encourage a larger intake of sweet food. In turn, this can cause health consequences like diabetes and dental problems. The test will identify your sugar sensitivity and preference towards consuming sugar-containing food.

Gene tested: SLC2A2

Proinsulin Conversion rate

A critical hormone in our body is made from a precursor protein called proinsulin in the pancreas. This hormone has a role in utilising glucose in the body. If an individual has a poor proinsulin conversion rate, there will be less of the hormone produced and a higher glucose level. High glucose in the blood can lead to diabetes and has long-term complications affecting other organs in our system. The test will identify your proinsulin conversion efficiency.

Genes tested :MADD, ACDY5, GLIS3

Fasting Blood Glucose

Fasting blood glucose is the glucose level in the blood after a period of not eating. If the level is high, it may indicate type II diabetes mellitus. The test will identify your susceptibility to having high fasting blood glucose levels and your genetic predisposition to type II diabetes mellitus.

Genes tested: G6P2C, ADRA2A, PROX1, GCK and SLC2A2

Glucose regulation

Hormone secretion is important in regulating the metabolism of Carbohydrates, Fats and Protein. The test will indicate the chance of pancreas dysfunction in secreting critical hormones that affect the regulation of blood glucose levels.

Genes tested:TCF7L2, SLC30A8, MTNR1B and Intergenic SNPs

Glucose uptake sensitivity

Sensitivity to certain hormones in our body affects the uptake of glucose by our cells. High sensitivity towards these hormones will increase the glucose uptake and reduce the chance of type II diabetes mellitus, and vice versa. The test will indicate your predisposition to type II diabetes mellitus.

Genes tested: NAT2 and Intergenic SNPs

What's the purpose of this DNA test?

The test is aimed to help you get a better understanding of your innate metabolism and how your body responds to certain nutrients and the way it converts food, vitamins and other nutrients. Implementing tailored changes into your diet and lifestyle can influence the time and effort needed to achieve your fitness goals.
 

Can I speak with a qualified specialist after receiving my reports?

Yes, you can look up the specialist you want to share your results with directly from your account, and book an appointment online. All within a few clicks on your portal.

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